This paper aims to find the optimal depot locations and vehicle routings for spare parts of an automotive company considering future demands.The capacitated location-routing problem (CLRP), which has been practiced by various methods, is performed to find the optimal depot locations and routings by additionally using the artificial neural network (
In this article, we analyse the impact of the introduction of options on an investment portfolio.Our first objective is to derive closed-form formulae for Reydon the standard measures of portfolio efficiency: risk premium, risk, Sharpe ratio, and beta, of any portfolio containing any combination of options.Using these formulae on three examples of
A quercetin derivative with remarkable biological performance was successfully synthesized by chemical modification of the flavonoid with docosahexaenoic acid to synthesize 2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate (3), deeply characterized by NMR spetrosco
We examined influence of the β-amyloid peptide (25-35) neurotoxic fragment (βAP) on Helix lucorum food-aversion learning.Testing with aversively conditioned carrot showed that 2, 5, and 14 days after training the βAP-injected group responded in a significantly larger number of cases and with a significantly smaller latency than the s
Draining peatlands to create agricultural land has been the norm in Europe, but in the context of climate change and the loss of biodiversity, these rich ecosystems may reactivate their functions as greenhouse gas sinks and retreat spaces for animals and plants.Against this background, the National Moor Rewetting Strategy was put into effect in Ger